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This web site covers: COLOSTRUM = IMMUNE FACTORS
IMMUNE FACTORS
Immunoglobulins, or antibodies, are the most important and
most prevalent immune factors in
bovine colostrum.
Immunoglogulins are found in all mammals, including humans,
and are divided into five classes
designated as IgA, IgD, IgE, IgG, and IgM. Each of these immunoglobulins
has its own individual functions, but overall they neutralize toxins, viruses,
and bacteria in the circulatory and lymphatic systems.
Immunoglobulins (sometimes called immunoglobins and gammaglobulins) are made of chains of large protein molecules composed of hundreds of amino acids. Immunoglobulins work separetely and together to destroy antigens. Some circulate in the blood and lymphatic systems: others reside in the mucous membranes and act as a barrier against invaders.
Immunoglobins are of critical importance because bacteria are becoming increasingly resistant to antibiotics, deadly bacteria infect our food supply, new viruses are multiplying faster than the vaccines to combat them, and bactderial infections are being linked with more diseases, including peptic ulcers and heart disease. In fact, the relationship between bacterial infection and heart disorders has strong evidence to support it. Colostrum and its rich supply of immunoglobulins may play a major role in combating this serious health problem.
The immunoglobins in bovine colostrum provide unique
protection against virtually all disease-causing organisms. It is unique
because the levels of immune factors in bovine colostrum are ten to twenty times
greater than those found in human colostrum. Why?
Human infants receive about half of their imminity from their mothers through
the placenta.
Calves, however, receive all of their initial immunity from colostrum, which
means bovine colostrum needs to be incredibly high in immune factors.
Those factors make it effective against many disease-causing organisms.
Your body can make good use of those immunoglobulins. As you read previously, the majority of your immunoglobulins are manufactured in the bowel. Bovine colostrum delivers its immunoglobulins to the bowel. It's a perfect match. Take IgG, for example. this is the most abundant immunoglobulin in bovine colostrum, and it is a key factor in the prevention and treatment of infectious diarrhea. Ideally, physicians use IgG to combat various other conditions, including anemia, chickenpox, chronic fatigue syndrome, hepatitis, multiple sclerosis, neutropenia, and systemic lupus.
Lactoferrin is a protein that binds with iron and has antiviral, anti-bacterial, and anti-inflammatory action. It defends the body against candidiasis, cancer, chronic fatigue syndrome, herpes, and other infections. Lactoferrin has a unique way of killing bacteria and supplying the body with iron at the same time. Bacteria need iron to reproduce. Lactoferrin attaches to iron and prevents bacteria from using it for their reproductive functions. Lactoferrin then gives the iron to the red blood cells, where it promotes a process that provides oxygen to the body's cells.
While lactoferrin is attached to bacteria, it also causes the bacterial membrane to become more porous, which allow the body's immune factors to more easily destroy the pathogens. Lactoferrin's anti-inflammatory activity is effective in vision disorders, while its antiviral properties help in the prevention and treatment of herpes, HIV, chronic fatigue syndrome, and other viral diseases. It also has shown promise against candida albicans, the yeast disorder that affects the lives of so many women. (added by webmaster = and for many men too.)
Proline-rich Polypeptide (PRP) regulates the kingpin of the immune network, the thymus gland, which produces T-cells. It also serves a critical role in regulating autoimmune disease by balancing the immune system response and toning down the overreaction that characterizes autoimmune disease. It does this by inhibiting overproduction of T-cells and lymphocytes, which leads to reduction in pain and swelling.
Lysozymes are potent hydrolyzing substances (agents that combine with water to produce a reaction) that enhances the function of the immune system. This compound is now added to infant formula to increase immune capability. Lysozymes are typically found in saliva, tears, and perspiration and are highly deadly to bacteria and viruses.
Cytokines are chemicals that are involved in cell-to-cell communication, antiviral and anti-tumor activity, and regulation of the duration and intensity of immune responses. They boost the activity of T-cells and stimulate production of immunoglobulins. Cytokines are composed of substances called interleukins, which scientists have numbered for convenience. One of them, interleukin-10, is a potent anti-inflammatory agent, which is useful for people with arthritis and other inflammatory disorders. In a study conducted by Alejandro Nitsch, MD, and Fabiola Nitsch, MD, in which they gave colostrum to patients with rheumatoid arthritis and osteoarthritis, and the doctors concluded that "the colostrum derived products contain ... agents that promote anti-inflammatory cytokine-type activity," and that "the most valuable aspect of this new therapeutic alternative is its profound effect on pain relief." Another, interleukin-2, has been used to treat some forms of cancer.
Glycoproteins and Trypsin Inhibitors help protect the immune and growth factors in colostrum from being destroyed by the digestive juices in the human gastrointestinal tract. Without these factors, bovine colostrum would not be effective in humans. Researchers have found that these inhibitors can prevent Helicobacter pylori from adhering to the stomach wall. Helicobacter pylori are bacteria responsible for causing peptic ulcer, gastric ulcer, and gastric cancer.
Lymphokines are hormone-like peptides that regulate the immune system response. Tumor necrosis factors are one type of lymphokine.
Oligo polysaccharides and Glycoconjugates are sugars that attract and bind to various pathogens and prevent them from entering or attaching themselves to the intestinal mucus membranes. With the assistance of other colostrum components, these sugars block the attachment of many disease-causing organisms, including Streptococcus pneumococci, E. coli and Salmonella, Entomoeba, Cryptosporidia, Giardia, Shigella, Clostridium difficile toxins A & B, and others.
Other immune factors in bovine colostrum include alpha 2-AP glycoprotein, alpha 1-antitripsin, alpha 1-fetoprotein, alpha 2-macroglubulin, albmin, B lactoglobulin, beta 2-microglogulin, C3, C4, enzymes, haemopexin, haptoglobin, lactopridoxase, orosomucoids, orotic acid,and prealbumin.